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Summarised Study: Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates.

This is a summarised study of "Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates" by Ruihua Wang, Yanfen Li, Wei Mu, Ziqiang Li, Jinxia Sun, Bo, Mi, Baohe Wang,, Zhong Zhong, Xiuzhen Luo, Chen Xie , Yuhong Huang. Published by Wolters Kluwer Health, Inc on 29 July 2018.

Mulberry leaf extract and blood sugar spikes Image credit:  Polina Tankilevitch

Study Methodology

The study involved 15 healthy volunteers given different combinations of mulberry leaf extract and carbohydrates (glucose, sucrose, maltose, and maltodextrin). They participated in a single-centre, randomised, open-label, 7-cycle self-controlled crossover study, which means that the volunteers have knowledge of the assigned treatment and will be switched throughout to all the treatment groups while the sequence of treatments is randomised for each person.

Reported improvements

The study demonstrated that the mulberry leaf extract significantly reduced the Glycemic Index values for the carbohydrates consumed.

  • maltose (53.11%)
  • sucrose (33.51%)
  • maltodextrin (31%)
  • glucose  (8.12%)

TL;DR

  • The study involved 15 healthy volunteers who were given different combinations of MLE, glucose, sucrose, maltose, and maltodextrin. 
  • Blood glucose levels were measured before and after carbohydrate intake at specific time intervals. 
  • The mulberry leaf extract (MLE ) reduced the GI values for the carbohydrates consumed significantly.
  • This is important because high-GI foods can cause larger fluctuations in blood glucose and insulin levels, which may be detrimental to individuals with diabetes or prediabetes.
  • By reducing the GI, MLE may help improve glycemic control and overall health.
  • MLE was well tolerated by the study participants, with no reported adverse events.
  • These results suggest that MLE could potentially be used to help reduce blood glucose levels after a meal, which could be particularly beneficial for individuals with diabetes mellitus.
  • Overall, these findings provide valuable insights into the potential benefits of MLE in managing blood glucose levels, especially for individuals with diabetes mellitus. However, further research is needed to validate and expand upon these observations. 
  • It's important to note that this study was exploratory in nature, and further studies with larger sample sizes are required to confirm and expand upon these findings.

Ready full study here.

— Ruihua Wang,Yanfen Li, Wei Mu, Ziqiang Li, Jinxia Sun, Bo Mi, Baohe Wang, Zhong Zhong, Xiuzhen Luo, Chen Xie , Yuhong Huang

Disclaimer

This content has been partially generated by artificial intelligence and should be used for informational purposes only. This content should not be considered as medical advice; always consult your doctor before starting new medication or supplements.

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